TGFβ3 - P8433M
/TGFβ3 - P8433M
Transforming growth factor TGFβ3 is a member of the TGF-β superfamily and regulates diverse cellular phenotypes. TGFβ3 binds to serine-threonine kinase type I and II receptors and activates signal transduction through SMAD2/3 proteins, thus regulating a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, and metabolism (Massagué; McDowell et al.). TGFβ3 enhances glycosaminoglycan production by mesenchymal stromal cells, stimulates scar-free healing, and improves glucose tolerance and phenotypic changes in adipocyte morphology (Hall et al.; Holton et al.). TGFβ3 induces proliferation of posterofrontal suture-derived mesenchymal stromal cells, and stimulates expression of FGF2 and FGF18 (James et al.).
- Quantity
Product Details
Size: 1 ml
Concentration: 1 mg/ml